Essay --

CHAPTER TWO 2.0 OVERVIEW OF THE DESCRIPTION, LIFE CYCLE OF TRYPANOSOME 2.1. Cell Structure of Trypanosome Trypanosomes are unicellular protozoan having a single flagellum that contains microtubules in the 9+2 arrangement typical of other flagella. At the base of the flagellum, the kinetoplast is found which contains DNA in the form of about 6000 connected circles. The kinetoplast DNA is 10% of the total cellular DNA where the action of some anti-trypanosome drugs occurs such as ethidium. The kinetoplast is part of the single long mitochondrion which undergoes structural changes during various stages of life cycle. The surface of the bloodstream form trypanosome contains a dense coat of variable surface glycoproteins (VSGs) which is replaced by an equally dense coat of procyclins when the parasite segregate into the procylic form in the tsetse fly midgut (Ogbadoyi et al., 2000). Trypanosome brucie a flagellated protozoan, is the causative parasite of the infectious disease known as African trypanosomiasis (African sleeping sickness) in African, while in America, Trypanosoma cruzi causes Chagas disease which is prevalent to human and animal, both are fatal when left untreated (Brun et al., 2010; Carlier et al.,2003; Pereira et al., 2011). African trypanosomiasis is the prominent causes of death in the 36 countries of sub-Saharan African at about 70,000 deaths yearly (Barrett et al., 2003; Keith, 2005). There are two subspecies of trypanosoma brucei that causes sleeping sickness to human which are Trypanosoma brucei gambiense, Trypanosoma brucei rhodesiense while African animal trypanosomiasis or nagana disease is caused by T. congolense, T. vivax and Trypanosoma brucei brucei . Trypanosoma brucei brucei is not infective to ... ...vade immune response) that occur in trypanosome. Thus, persistent infection in the host results to continuity in cycle of trypanosome replication, immune complex development, and changing surface coat glycoprotein (Taylor and Authie, 2004; Sinshaw et al., 2006). The clinical signs of AAT are an intermittent fever, signs of anemia, lymphadenopathy, anaemia, anorexia, dullness, inactivation, depression, loss of milk and meat production, and death in un-treated cases and weight loss. In the pathogenesis of trypanosomiasis, immunosuppression is the most important and complicating factor caused by trypanosomes to their host. It is difficult to conclude which clinical signs are owing to a given parasite and only few studies have been made in this aspect to identify a specified sign to particular trypanosomes (Murray and Dexter, 1988; Garner et al., 2003).

The Moral Component of Rerum Novarum

1. What did Leo say about the poor people? The present age has handed over the working poor to inhumane employers and greedy competitors. (a. 6) He saw the working poor as needy and helpless, (a. 66) And they are insufficiently protected against injustices and violence. (a. 32) 2. What did he want the working poor to understand? He wanted the working poor to understand that the lowest in society cannot be made equal with the highest and that poverty is no disgrace. (a. 37) To suffer and endure is human. (a. 27) The working poor are told not to injure the property or person of their employers and not to forcibly the property of others. (a. 55) 3. What was the moral component of Leo's message? The message to the working poor seems to be aimed at calming and consoling the poor, encouraging them to accept their position in society without rancor and without harm to others. Leo sought to enlist the aid of the working poor in preserving good order. 4. What did Leo say to those who work with the poor? Leo XIII declared that the working poor must be cared for. Employers have clear moral obligations: workers are not to be treated as slaves; the dignity of your workers' human personality must be respected; do not use people as things for gain; do not oppress the needy or the wretched for your own profit. The approach to employers is on a high moral plane, but it is also very practical: you need your poor worker, so work with him harmoniously. It is immoral to treat workers unjustly, and it is also not in the best interest of ownership and management. 5. What was the message to the employers? Leo warns the employers against the pitfalls of being wealthy; pointing out that wealth does not end sorrow and that it is a hindrance to eternal happiness. In view of eternity, what counts is not how much we have but how we use what we have, and we will have to account to God for our use of wealth 6. What did the Pope say to the wealthy? The wealthy are told that their goods are for their perfection and the benefit of others, and they are encouraged to share their goods when they see others in need: when the need is extreme, the demand is of justice: otherwise, the demand is of charity. 7. What was R.N's teachings of unions and strikes? The encyclical comes down strongly in favour of unions, stating that their increase is to be desired. (a. 69) The immediate object of unions is the private advantage of those associated, so that workers are to use their unions to secure increase in goods of body, soul and prosperity. (a. 71) The principal goal of unions is moral and religious perfection. (a. 77) The message about preserving good order is clear and unmistakable, but so is the message about standing up for rights. Leo XIII wanted the working poor to protect their interests, to make demands, to press their claims, and the principal means for doing this was the formation of unions. 8. What did Leo say about working conditions? Wages should never be less than enough to support a worker who is thrifty and upright. (a. 63) Work should not be so long that it dulls the spirit or that the body sinks from exhaustion. (a. 59) The factors in the establishment of hours are listed as: the nature of the work; the circumstances of time and place; the physical condition of the workers. (a. 59) 9. What was his stand on private ownership and property? Private ownership must be preserved inviolate. (a. 23) Must be regarded as sacred. (a. 65) It is wrong for ownership to be limited to a small number of people, and private property must be spread among the largest number of population. (a. 65) And a more equitable division of goods. (a. 66) 10. How did Leo see the role of government? The purpose of government is to cause public and individual well-being. (a. 48) The government must protect the community and it's constituent parts. (a. 52) Protect equitably each and every class of citizens. (a. 49) Give special consideration to the weak and poor. (a. 54) This special care should include the working poor. (a. 54) Improve the condition of workers. (a. 48) Safeguard the well-being and interests of workers. (a. 49) Protection of the goods of the worker's soul. (a. 57) The government's intervention in matters of wages, hours, and working conditions should be avoided. (a. 64) The government does not have the authority to forbid unions. (a. 72) It can oppose, dissolve and prevent unions when their objective is at variance with good morals, justice, or to it that there are no strikes. (a. 56) It should seek to remove the causes of strikes. (a. 56) Government must permit freedom of action to individuals and families. (a. 52) Government should give public aid to families in extreme difficulty. (a. 21) Â · Briefly summarise the popes intention and purpose for the Rerum Novarum. The Popes intention was his conviction that the present ages has handed over the working poor to inhumane employers and greedy competitors. He wanted to help the working poor by setting these rules. These rules help people to know their roles and obligations when dealing with work.

Adolf Hitler, The Leader Of The Nazi Party - 1153 Words

Adolf Hitler, the leader of the Nazi Party, had his army kill 6-11 million people. These victims varied from gypsies, homosexuals, handicapped, Jews, and more. As stated by Adolf on his autobiography Mein Kampf, he believed that he was doing God’s work by exterminating the Jews. â€Å"...By defending myself against the Jew, I am fighting for the work of the Lord.† (Mein Kampf). His early life, education, and military training all have a crucial role in his rise to power during WWII. Hitler was born on April 20, 1889 in Braunau, Austria to Klara and Alois Hitler (History.com). He was a popular boy in primary school, but unacknowledged to his pupils in secondary school. He slacked in school and dropped out at the age of 15 (History.co). â€Å"His†¦show more content†¦He had a dream of going to a classical school and becoming an artist, but his father sent him to technical high school in Linz in September 1900 (Historyplace.com). He dropped out at the age of fift een because he did not enjoy it (Historylearningsite.co). â€Å"I thought that once my father saw how little progress I was making at the technical school, he would let me devote myself to my dream, whether he liked it or not† (Hitler, 5). After dropping out of technical high school, he tried to be an artist but was rejected. â€Å"He was convinced that it was a Jewish professor that had rejected his art work†¦Ã¢â‚¬  (Trueman, 1). Afterwards, he tries to join the Austrian military, but is too weak (Historylearningsite.co). He moves to Germany because he is qualified for the German military and has military training there (Historylearningsite.co). His task was to carry messages to officers behind the front line. The Treaty of Versailles had affected him, which angered him (Historylearningsite.co). Therefore, one of his main goals was to destroy the Treaty of Versailles (History.com). The Nazi Party was â€Å"A German party founded in 1919 and led from 1921 by Hitler. I t took power when Hitler was offered the post of chancellor in 1933 and dominated German life until its collapse at the end of World War II†